The building at 2270 North Humboldt Street was constructed in 1965 and dedicated as the George Washington Carvery Day Nursery in 1966. The Nursery organization dates back to 1916 when it was first organized by the Negro Women’s Club Home Association of Denver. Like the nursery, the women’s club was also brand new. It was formed by the coming together of seven African American woman’s clubs with the intent of establishing a “club home where young black women might stay,” centering around the ideas of “a nursery, employment, education, and rights of arrested black children.”

After a fundraising campaign, the group first moved into a two-story house at 2357 Clarkson Street. The nursery proved successful, and by 1921, was caring for thirty children. Around 1946-1948 (sources mention different years) the nursery changed its name to the George Washington Carver Day Nursery. In April of 1964, the organization kicked off another campaign to raise $80,000 for a new building.  In 1966, the nursery moved to its larger quarters at 2270 Humboldt Street and operated there for some time